High sensitivity photonic crystal biosensor incorporating nanorod structures for enhanced surface area

نویسندگان

  • Wei Zhang
  • Nikhil Ganesh
  • Ian D. Block
  • Brian T. Cunningham
چکیده

The surface area of a photonic crystal biosensor is greatly enhanced through the incorporation of a porous TiO2 film possessing the structure of nanorods into the device. The film is deposited by the glancing angle deposition technique in an e-beam evaporation system. The sensitivity of high surface area sensors is compared with sensors without the high surface area coating. Results for detection of polymer films, large proteins and small molecules indicate up to a four-fold enhancement of detected adsorbed mass density. © 2007 Elsevier B.V. All rights reserved.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Two-curve-shaped biosensor using photonic crystal nano-ring resonators

We design a novel nano-ring resonator using two-dimensional photonic crystal (2D-PhC), for bio-sensing applications. The structure of biosensor is created by two-curve-shaped ring resonator which sandwiched by two waveguides. These are configured by removing one row of air holes. The refractive index of sensing hole is changed by binding an analyte. Hence, intensity of the transmission spectrum...

متن کامل

Photonic crystal microring resonator for label-free biosensing.

A label-free optical biosensor based on a one-dimensional photonic crystal microring resonator with enhanced light-matter interaction is demonstrated. More than a 2-fold improvement in volumetric and surface sensing sensitivity is achieved compared to conventional microring sensors. The experimental bulk detection sensitivity is ~248nm/RIU and label-free detection of DNA and proteins is reporte...

متن کامل

Enhanced fluorescence on a photonic crystal surface incorporating nanorod structures.

Fluorescence has long been recognized as an important tool for probing biological structure and function. Development of optically active structures that can enhance fluorescence intensity has gained much attention as a means for detecting fluorescent-tagged analytes at low concentrations for applications in DNA expression analysis and protein diagnostic assays. The majority of structures devel...

متن کامل

Temperature Tunability of Dielectric/ Liquid Crystal / Dielectric Photonic Crystal Structures

Recently, photonic crystals doped with liquid crystal (LC) material havegained much research interest. In this article new ternary one-dimensional photoniccrystal introduced and studied. The liquid crystal layer of 5CB and 5PCH is sandwichedby two dielectric layers. For the first time, we use four structures SiO2/UCF35/CaF2,SiO2/5CB/CaF2, NFK51/UCF35/NPSK53 and NFK51/5CB/NPSK53. The effect ofte...

متن کامل

Spatially selective photonic crystal enhanced fluorescence and application to background reduction for biomolecule detection assays

By combining photonic crystal label-free biosensor imaging with photonic crystal enhanced fluorescence, it is possible to selectively enhance the fluorescence emission from regions of the PC surface based upon the density of immobilized capture molecules. A label-free image of the capture molecules enables determination of optimal coupling conditions of the laser used for fluorescence imaging o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2008